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Type:   Micro Organ/System:   Heart Description:   HEART: Vessels, saphenous vein coronary bypass graft: Atherosclerosis: Micro EVG low mag rather large necrotic atheroma with little hemorrhage no fibrous cap moderate fibrous intimal thickening 30 mo post-op © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Vessels, saphenous vein coronary bypass graft: Atherosclerosis: Micro plastic section at low mag shows layers of wall very well and vascularization in wall diffuse intimal thickening well shown rather large mass of subendothelial foam cells without necrosis outside case history not known © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Vessels, saphenous vein coronary bypass graft: Atherosclerosis: Micro trichrome low mag large plaque with necrotic foam cells and hemorrhage showing erosion into thickened intima 39 mo post-op © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Vessels, saphenous vein coronary bypass graft: Atherosclerosis: Micro EVG low mag large number subendothelial foam cells showing erosion into thickened intima no necrosis evident bizarre foam cells 72 mo post-op © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Vessels, saphenous vein coronary bypass graft: Atherosclerosis: Micro H&E med mag foam cells eroding into thickened intima no necrosis hyalinized intimal connective tissue 72 mo post-op © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Vessels, saphenous vein coronary bypass graft: Atherosclerosis: Micro H&E med mag portion of advanced plaque lesion showing necrosis with hemorrhage and fibrin 72 mo post-op © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Vessels, saphenous vein coronary bypass graft: Atherosclerosis: Micro trichrome low mag advanced plaque with hemorrhage and necrosis outside case © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Vessels, saphenous vein coronary bypass graft: Atherosclerosis: Micro trichrome low mag advanced plaque lesion with hemorrhage and necrosis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Vessels, saphenous vein coronary bypass graft: Atherosclerosis: Micro trichrome low mag very complicated hemorrhagic and necrotic plaque with lumen occlusion by what appears to be recanalized thrombus and a large aneurysm at side filled with old blood and atheroma crystals © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Vessels, saphenous vein coronary bypass graft: Atherosclerosis: Micro H&E low mag ruptured hemorrhagic and necrotic plaque basophilic material may be contrast media 48 mo post-op 81 © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Vessels, saphenous vein coronary bypass graft: Atherosclerosis: Micro H&E low mag necrotic ruptured atheromatous plaque 48 mo post-op 81 © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Vessels Description:   VESSELS: Coronary artery: Atherosclerosis: Micro H&E low mag complicated hemorrhagic necrotic and thrombosed lesion thrombus present probably for weeks at least © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag good demonstration of necrotic fibers with macrophages cleaning up debris 5 to 7 day lesion © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag good demonstration of macrophages cleaning up necrotic fibers 5 to 7 day lesion © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag good demonstration of macrophages cleaning up necrotic fibers 5 to 7 day lesion © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent demonstration of macrophages cleaning up necrotic myofibers 5 to 7 day old lesion © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro H&E low mag subendocardial myocytolysis apparent extensive subendocardial necrosis and dilated vessels © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro H&E high mag subendocardial myocytolysis and extensive myonecrosis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro ald fusch high mag subendocardial myocytolysis and extensive myonecrosis same as slide 92 © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro ald fusch high mag subendocardial fibrosis with necrosis and dropout of myofibers rather classic chronic ischemia © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro ald fusch low mag subendocardial myocytolysis dilated vessels extensive necrosis is present but is not evident in this slide © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E necrosis with extensive macrophage removal of dead myofibers no evidence of fibrosis good example probably about 7 days © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent example edge of infarct with extensive contraction band necrosis and neutrophils © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent example edge of infarct with extensive contraction band necrosis and neutrophils © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent example edge of infarct with extensive contraction band necrosis and neutrophils © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E med mag edge of acute infarct with intense neutrophil infiltrate with necrosis of neutrophils about 72 hours © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E med mag necrotic myocardium with wavy fiber change © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag necrotic myocardium can see some karyolysis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro trichrome med mag necrotic myocardium no cell infiltrate can see some karyolysis © University of Alabama at Birmingham, Department of Pathology

Image# 124 Search Again  |  Download Tips  |  View Cart

Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent example edge of infarct with intense neutrophil infiltrate necrosis of neutrophils about 72 hours © University of Alabama at Birmingham, Department of Pathology

Image# 125 Search Again  |  Download Tips  |  View Cart

Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent edge of infarct with abundant neutrophils and some contraction band necrosis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent edge of infarct with neutrophils and karyolysis in necrotic myocardium neutrophils show necrosis © University of Alabama at Birmingham, Department of Pathology

Image# 128 Search Again  |  Download Tips  |  View Cart

Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent edge of infarct with neutrophils showing necrosis © University of Alabama at Birmingham, Department of Pathology

Image# 129 Search Again  |  Download Tips  |  View Cart

Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro trichrome high mag necrotic myocardium with neutrophil infiltrate showing necrosis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro trichrome high mag necrotic myocardium with neutrophil infiltrate © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag necrotic myocardium show karyolysis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag necrotic myofibers with some contraction bands and fibrin in interstitial space © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag necrotic myocardium nuclear debris in interstitial space © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag necrotic myofibers showing preservation of cross striations © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro trichrome necrotic myofibers showing preserved cross striations © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro trichrome necrotic myofibers showing preserved cross striations © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Miliary Infarction: Micro H&E high mag contraction band necrosis miliary infarction lesion good example © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag acute subendocardial necrosis contraction band type few neutrophils © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro trichrome high mag edge of infarct several days old showing lipofuscin pigment in macrophages derived from necrotic myofibers © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Miliary Infarction: Micro H&E high mag excellent contraction band necrosis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Miliary Infarction: Micro H&E high mag outstanding example of focal contraction band necrosis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent example necrotic myofibers and heavy neutrophil infiltrate 48 hour lesion © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent example necrotic fibers and heavy neutrophil infiltrate 48 hour lesion © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent example of myofiber necrosis with eosinophilia and adjacent non-infarcted muscle to compare with neutrophil infiltrate is mild guess lesion about 48 hours © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent example myofiber necrosis with eosinophilia and adjacent non-infarcted muscle for comparison few neutrophils guess 48 hours © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro H&E low mag subendocardial myocytolysis large area of necrotic myofibers beneath endocardium with inflammatory cell infiltrate in the center of the lesion © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro H&E low mag subendocardial myocytolysis necrosis of muscle in trabecula some inflammatory cell infiltrate in center of lesion © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent example of macrophages at edge of healing infarct necrotic muscle well shown © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag excellent depiction of edge of acute infarct with contraction band necrosis few inflammatory cells © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag necrotic myofibers with intense neutrophilic infiltrate and necrosis of neutrophils lesion about 72 hours © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag necrotic myofibers with intense neutrophil infiltrate and necrosis of neutrophils about 72 hours © University of Alabama at Birmingham, Department of Pathology

Image# 231 Search Again  |  Download Tips  |  View Cart

Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro H&E med mag subendocardial band of muscle that usually shows myocytolysis shows marked atrophy and loss of muscle fibers subendocardial myocardium is necrotic good chronic ischemia lesion © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro H&E low mag massive subendocardial myofiber necrosis same section as slide 231 but lower in mag © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro H&E med mag macrophage removal and early fibrous scar at edge of large area of myofiber necrosis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro H&E low mag subendocardial myocytolysis and extensive necrosis with inflammatory cells in center of lesion © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Respiratory Description:   RESPIRATORY: Lung: Pneumonia: Micro H&E low mag severe bronchopneumonia with necrosis early abscess formation © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Respiratory Description:   RESPIRATORY: Lung: Pneumonia: Micro H&E low mag severe bronchopneumonia with necrosis and early abscess © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Urinary tract Description:   URINARY TRACT: Kidney: Acute Tubular Necrosis: Micro H&E high mag good example © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Urinary tract Description:   URINARY TRACT: Kidney: Acute Tubular Necrosis: Micro H&E high mag good example © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Urinary tract Description:   URINARY TRACT: Kidney: Acute Tubular Necrosis: Micro H&E high mag excellent example © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Urinary tract Description:   URINARY TRACT: Kidney: Acute Tubular Necrosis: Micro H&E high mag excellent example © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Blood-RES Description:   BLOOD-RES: Spleen: Metastatic Carcinoma: Micro H&E med mag good example of necrosis in a malignant tumor © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Muscle-Soft tissue Description:   MUSCLE-SOFT TISSUE: Skeletal muscle: Abscess: Micro H&E high mag marked shock necrosis in muscle and abscess due to Candida leukemia case © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Abscess: Micro H&E high mag abscess due to Candida with marked muscle necrosis leukemia case © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E low mag good subendocardial infarct with neutrophils in endocardium subendocardial myocytolysis and coagulation necrosis with neutrophils a rather classic lesion © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E very low mag excellent infarct with polys edema and coagulation necrosis forming mural thrombus can see easy even at this very low mag © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro H&E high mag excellent example myocytolysis beneath endocardium and further in coagulation necrosis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro trichrome high mag very good example myocytolysis at margin of area of coagulation necrosis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag hypertrophied and polyploid and multinucleated myofibers at margin of infarct or area of chronic ischemia causing necrosis an excellent example © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag hypertrophied and polyploid myofibers at margin of infarct or necrosis due to chronic ischemia © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag hypertrophied and polyploid myofibers at margin of infarct or area of necrosis due to chronic ischemia one cell is multinucleated © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Myocardial Infarct: Micro H&E high mag hypertrophied and polyploid cells at margin of infarct or area of necrosis due to chronic ischemia a good example © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro trichrome high mag good example myocytolysis endocardium is thickened myocardium internal to layer with myocytolysis shows necrosis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Heart Description:   HEART: Chronic Ischemia: Micro H&E very low mag excellent example of extensive myocytolysis and focal small areas of necrosis © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Nervous system Description:   NERVOUS SYSTEM: Brain: Shock: Micro H&E high mag ischemic necrosis of neurons © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Nervous system Description:   NERVOUS SYSTEM: Brain: Shock: Micro H&E high mag ischemic necrosis of neurons good © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Nervous system Description:   NERVOUS SYSTEM: Brain: Shock: Micro H&E high mag ischemic necrosis of neurons good © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Nervous system Description:   NERVOUS SYSTEM: Brain: Shock: Micro H&E high mag ischemic necrosis neurons good © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Endocrine Description:   ENDOCRINE: Adrenal: Herpes: Micro H&E high mag focal necrosis in adrenal cortex due to herpes simplex infection in newborn © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Endocrine Description:   ENDOCRINE: Adrenal: Herpes: Micro H&E low mag focal necrosis in cortex due to herpes simplex infection in newborn © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Liver-Biliary Description:   LIVER-BILIARY: Herpes: Micro H&E low mag extensive hemorrhage and necrosis nonspecific © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Liver-Biliary Description:   LIVER-BILIARY: Herpes: Micro H&E high mag focal necrosis inclusions present but difficult to find © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Liver-Biliary Description:   LIVER-BILIARY: Herpes: Micro H&E high mag focal necrosis giant cell formation necrosis and difficult to find inclusions © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Nervous system Description:   NERVOUS SYSTEM: Brain: Shock: Micro H&E high mag neuronal necrosis in dentate nucleus due to ischemia © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Nervous system Description:   NERVOUS SYSTEM: Brain: Shock: Micro H&E high mag neuronal necrosis in dentate nucleus good example © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Nervous system Description:   NERVOUS SYSTEM: Brain: Shock: Micro H&E high mag neuronal necrosis in dentate nucleus good example © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Nervous system Description:   NERVOUS SYSTEM: Brain: Shock: Micro H&E high mag neuronal necrosis in dentate nucleus © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Alimentary tract Description:   ALIMENTARY TRACT: Small intestine: Shock: Micro H&E low mag shows necrosis hemorrhage and congested submucosal vessels © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Alimentary tract Description:   ALIMENTARY TRACT: Small intestine: Shock: Micro H&E med mag marked necrosis in mucosa and submucosa with severe interstitial hemorrhage a very good example © University of Alabama at Birmingham, Department of Pathology

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Type:   Micro Organ/System:   Respiratory Description:   RESPIRATORY: Lung: Metastatic Carcinoma: Micro H&E med mag choriocarcinoma with extensive necrosis © University of Alabama at Birmingham, Department of Pathology